10 datasets

ZivaHub2026 · dataset

<p dir="ltr">Lung adenocarcinoma (LUAD) is highly heterogeneous, and the mechanisms linking gut microbiota-derived metabolites to tumor-associated transcriptional regulation remain unclear. We integrated two paired LUAD transcriptomic datasets, GSE40419 and GSE32863, to perform differential expression, functional enrichment, protein-protein interaction (PPI), and transcription factor (TF) activity

ZivaHub + HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue

<p dir="ltr">Primary sclerosing cholangitis (PSC) is a progressive cholangiopathy tightly linked to gut microbiota dysregulation via the gut-liver axis. While mesenchymal stromal cell (MSC) therapy holds promise for PSC, whether and how the gut microbiota mediates its efficacy remain unknown. Using Mdr2⁻/⁻ mice, we found that human placenta‑derived MSCs significantly alleviated PSC symptoms, reduc

HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue

<p dir="ltr"><b>Background</b>: Optimising sampling frames for genomic surveillance of <i>E. coli</i> and <i>Klebsiella </i>may support interventions to mitigate bloodstream infections (BSIs), but approaches to estimating sample size and how these relate to bacterial population diversity at multiple genetic levels (strain/plasmid/antimicrobial resistance genes</p><p dir="ltr">[ARGs]) are lacking.<

figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p dir="ltr">This repository accompanies the systematic review “Pyomelanin in <i>Pseudomonas aeruginosa</i>: a systematic review of genetic architectures, evolutionary trade-offs and clinical relevance”. It contains study-level data extracted from 50 included studies, mapped-deletion data and the Supplementary Information.</p>

figshare2026 · Astronomical catalogue · restricted

<p dir="ltr"><i>Bacteroides</i> <i>fragilis</i> group (BFG) organisms are important members of the gut commensal flora and common anaerobic pathogens causing various infections. Traditionally, antimicrobial susceptibility patterns in BFG have been highly predictable, leading to generally good outcomes with empirical treatment. However, in recent years, resistance to several key anti-anaerobic drug

figshare2026 · Astronomical catalogue

<p dir="ltr">Data set resistance</p><p dir="ltr"><br></p>

figshare2026 · Astronomical catalogue

<p dir="ltr">QFT-Plus assay results over three years using three different methodologies: ELISA-based testing and CLIA-based testing with either lyophilized or liquid conjugate formulations in routine clinical practice.</p>

figshare2026 · Astronomical catalogue

<p dir="ltr">Supplementary Materials for 'β-Lactamase Type, Multidrug Resistance and the Association with Virulence in Third-Generation Cephalosporin-Resistant <i>Klebsiella pneumonia</i><i>e</i>'</p>

figshare2026 · Astronomical catalogue

<p dir="ltr">This study compared the VITEK® REVEAL^TM fast AST system for direct testing from positive blood cultures (PBCs) with the standard-of-care VITEK® 2.A total of 250 prospectively collected PBC bottles containing monomicrobial Gram-negative organisms were assessed. AST was performed using VITEK® REVEAL^TM directly from PBC and VITEK® 2 from isolated colonies recovered

figshare2026 · Astronomical catalogue

<p dir="ltr">16srRNA sequencing. </p>