422 datasets

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Introduction<p>Low birth weight (LBW) remains a major public health challenge globally, particularly in low- and middle-income countries (LMICs). In Ghana, socioeconomic and regional inequalities in birth outcomes persist. This study examined LBW prevalence, socioeconomic and regional inequalities, and factors associated with LBW using nationally representative data.</p>Methods<p>A secondary analy

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

Background<p>Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease associated with substantial morbidity and increased mortality. Although several composite inflammatory indices have been proposed as accessible biomarkers, their associations with RA and long-term prognosis remain incompletely understood.</p>Methods<p>We analyzed 15,545 adults from five NHANES cycles (2001–2010), inc

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

Background<p>Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease associated with substantial morbidity and increased mortality. Although several composite inflammatory indices have been proposed as accessible biomarkers, their associations with RA and long-term prognosis remain incompletely understood.</p>Methods<p>We analyzed 15,545 adults from five NHANES cycles (2001–2010), inc

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

Background<p>Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease associated with substantial morbidity and increased mortality. Although several composite inflammatory indices have been proposed as accessible biomarkers, their associations with RA and long-term prognosis remain incompletely understood.</p>Methods<p>We analyzed 15,545 adults from five NHANES cycles (2001–2010), inc

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing

<p>Congenital melanocytic naevi (CMN) are usually associated with activating alterations in NRAS or BRAF, but some extensive lesions lack detectable canonical hotspot variants. We report a 9-year-old boy with a large craniofacial CMN involving the face, scalp, upper eyelid and bulbar conjunctiva, with deep extension, mechanical ptosis and secondary amblyopia. Histology showed benign dermal melanoc

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

Background<p>Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease associated with substantial morbidity and increased mortality. Although several composite inflammatory indices have been proposed as accessible biomarkers, their associations with RA and long-term prognosis remain incompletely understood.</p>Methods<p>We analyzed 15,545 adults from five NHANES cycles (2001–2010), inc

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

Introduction<p>Low birth weight (LBW) remains a major public health challenge globally, particularly in low- and middle-income countries (LMICs). In Ghana, socioeconomic and regional inequalities in birth outcomes persist. This study examined LBW prevalence, socioeconomic and regional inequalities, and factors associated with LBW using nationally representative data.</p>Methods<p>A secondary analy

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

Background<p>Cardiovascular diseases remain a leading global health threat. Recent advances in room-temperature sensing and artificial intelligence (AI) have renewed research interest in the clinical translation of magnetocardiography (MCG) for cardiovascular diagnosis, yet the global research evolution of MCG has yet to be quantitatively characterized.</p>Methods<p>Literature from the Web of Scie

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

Background<p>Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease associated with substantial morbidity and increased mortality. Although several composite inflammatory indices have been proposed as accessible biomarkers, their associations with RA and long-term prognosis remain incompletely understood.</p>Methods<p>We analyzed 15,545 adults from five NHANES cycles (2001–2010), inc

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Background<p>This study investigated the associations of multiregional macular and peripapillary OCTA metrics and systemic hematologic biomarkers with 12-month diabetic retinopathy progression and evaluated whether their combination improved prognostic discrimination.</p>Methods<p>This single-center longitudinal cohort study included 55 adults with type 2 diabetes and established DR, contributing

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

Introduction<p>Low birth weight (LBW) remains a major public health challenge globally, particularly in low- and middle-income countries (LMICs). In Ghana, socioeconomic and regional inequalities in birth outcomes persist. This study examined LBW prevalence, socioeconomic and regional inequalities, and factors associated with LBW using nationally representative data.</p>Methods<p>A secondary analy

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Objective<p>To characterize the clinical, serologic, and treatment features of patients with obstetric antiphospholipid syndrome (OAPS), determine the proportion meeting the laboratory domain of the 2023 American College of Rheumatology/European Alliance of Associations for Rheumatology (ACR/EULAR) classification criteria, and examine patients identified through non-criteria antibodies.</p>Methods

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Background<p>Chronic obstructive pulmonary disease (COPD) is increasingly recognised as a systemic condition in which metabolic dysfunction may influence disease severity and exacerbation risk. The combined effects of insulin resistance and leptin dysregulation on COPD outcomes remain incompletely defined. This study evaluated their associations with exacerbation burden, airflow limitation and pat

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

Background<p>Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease associated with substantial morbidity and increased mortality. Although several composite inflammatory indices have been proposed as accessible biomarkers, their associations with RA and long-term prognosis remain incompletely understood.</p>Methods<p>We analyzed 15,545 adults from five NHANES cycles (2001–2010), inc

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

Background<p>Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease associated with substantial morbidity and increased mortality. Although several composite inflammatory indices have been proposed as accessible biomarkers, their associations with RA and long-term prognosis remain incompletely understood.</p>Methods<p>We analyzed 15,545 adults from five NHANES cycles (2001–2010), inc

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

Background<p>Superficial vein thrombosis (SVT) is a clinically relevant complication of lower extremity varicose veins. This study aimed to develop and internally validate a parsimonious nomogram for estimating the probability of concurrent SVT at presentation.</p>Methods<p>This single-center retrospective study included 423 patients with lower extremity varicose veins, including 91 with SVT. Twen

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

Introduction<p>Low birth weight (LBW) remains a major public health challenge globally, particularly in low- and middle-income countries (LMICs). In Ghana, socioeconomic and regional inequalities in birth outcomes persist. This study examined LBW prevalence, socioeconomic and regional inequalities, and factors associated with LBW using nationally representative data.</p>Methods<p>A secondary analy

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

Background<p>Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease associated with substantial morbidity and increased mortality. Although several composite inflammatory indices have been proposed as accessible biomarkers, their associations with RA and long-term prognosis remain incompletely understood.</p>Methods<p>We analyzed 15,545 adults from five NHANES cycles (2001–2010), inc

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

Background<p>Complement activation is a key driver of disease progression in IgA nephropathy (IgAN). While previous syntheses were limited to phase II evidence, pivotal phase III data—including the 24-month results of the APPLAUSE-IgAN trial—have recently emerged, necessitating an updated appraisal of complement-targeted therapies.</p>Methods<p>We conducted a systematic literature search in PubMed

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

Objective<p>To characterize the clinical, serologic, and treatment features of patients with obstetric antiphospholipid syndrome (OAPS), determine the proportion meeting the laboratory domain of the 2023 American College of Rheumatology/European Alliance of Associations for Rheumatology (ACR/EULAR) classification criteria, and examine patients identified through non-criteria antibodies.</p>Methods

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

Background<p>Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease associated with substantial morbidity and increased mortality. Although several composite inflammatory indices have been proposed as accessible biomarkers, their associations with RA and long-term prognosis remain incompletely understood.</p>Methods<p>We analyzed 15,545 adults from five NHANES cycles (2001–2010), inc

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Objective<p>Surfactant replacement therapy (SRT) remains a cornerstone of neonatal respiratory management, but contemporary national data on temporal trends in SRT use across gestational age groups in the United States remain limited. We aimed to characterize gestational age–specific SRT rates among U.S. live-born infants and assess temporal trends over time.</p>Study design<p>We conducted a seria

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Background<p>Endoscopic retrograde cholangiopancreatography (ERCP) is associated with several adverse events, of which post-ERCP pancreatitis (PEP) is the most frequent despite established preventive measures. Clinical reviews evaluate risk factors and interventions, but the organization and development of the research field have received less attention. This study examined the development of the

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

Background<p>Endoscopic retrograde cholangiopancreatography (ERCP) is associated with several adverse events, of which post-ERCP pancreatitis (PEP) is the most frequent despite established preventive measures. Clinical reviews evaluate risk factors and interventions, but the organization and development of the research field have received less attention. This study examined the development of the

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

Background<p>Endoscopic retrograde cholangiopancreatography (ERCP) is associated with several adverse events, of which post-ERCP pancreatitis (PEP) is the most frequent despite established preventive measures. Clinical reviews evaluate risk factors and interventions, but the organization and development of the research field have received less attention. This study examined the development of the