ZivaHub + Deakin Research Online + DMU Figshare2026 · dataset
Investigating pathology associated with cardiac hypertrophy at the single-cell level…<br><br>This PhD thesis aimed to characterise dysregulated gene expression in distinct cardiac cell types during pathological CH using single-cell RNA-sequencing.… …<br><br>After devising a bioinformatic technique to systematically assess conservation in mouse-human cardiac gene expression, dysregulated expression was characterised at the single-cell…
ScienceDB2026 · dataset · unknown
Aging-related psoriasis combined with heart failure dataset…Single-cell in silicoknockdown analysis was performed using the PSO dataset GSE20201 and the HF dataset GSE298023.After excluding irrelevant samples, the PSO training set comprised… …49 samples, including 35 PSO cases and 14 healthy controls; the PSO test set comprised 170 samples, including 85 PSO cases and 85 healthy controls; and the PSO single-cell dataset included…
ZivaHub + Deakin Research Online + DMU Figshare2026 · dataset · unknown
Biophysical correlates of base-mediated radiation cardiotoxicity in non-small cell lung cancer…This thesis investigates the base-mediated radiation cardiotoxicity observed in the radical treatment of non-small cell lung cancer (NSCLC).… …The published clinical experience is limited to small, single-centre clinical cohorts, or large, data-mining analyses, and typically include inadequate levels of cardiovascular co-morbidity…
NASA Data Portal2026 · Astronomical catalogue · unknown
Spaceflight induces systemic effects on extracellular matrix and immune system in different age-stages - Heart atria data…To explore molecular changes, we generated a single-cell RNA sequencing dataset, of 216 samples from 28 mouse organs and tissues under spaceflight and control conditions.… …drives age-independent systemic changes, primarily affecting tissue remodeling and alterations in cytoskeleton, membrane and extracellular matrix (ECM), particularly in endothelial cells…
NASA Data Portal2026 · Astronomical catalogue · unknown
Spaceflight induces systemic effects on extracellular matrix and immune system in different age-stages - Heart ventricles data…To explore molecular changes, we generated a single-cell RNA sequencing dataset, of 216 samples from 28 mouse organs and tissues under spaceflight and control conditions.… …drives age-independent systemic changes, primarily affecting tissue remodeling and alterations in cytoskeleton, membrane and extracellular matrix (ECM), particularly in endothelial cells…
ZivaHub + Deakin Research Online + DMU Figshare2026 · dataset
ISG15 signalling in coronary microvascular endothelial cells as a key determinant of adverse remodelling in diabetic cardiomyopathy…cardiomyopathy (DCM), characterised by subclinical diastolic dysfunction, microvascular injury, and heightened susceptibility to cardiac stress, is a major contributor to chronic heart… …<br><br>Methods: Differential gene expression analyses were performed on cardiac tissue from an established mouse model of DCM using single nuclei and total RNA sequencing.…
ScienceDB2025 · dataset · restricted
2023 Ultrasound/Laboratory Examination Data for Individuals Aged 65 and Over in Guangxi Single Center…disease (1 for yes, 0 for no), systolic blood pressure (mmHg), diastolic blood pressure (mmHg), waist circumference (cm), body mass index (BMI, kg/m²), heart rate (beat/min),… …for yes, 0 for no), smoking status (2 for current smoker, 1 for former smoker, 0 for non-smoker), alcohol consumption habits (1 for yes, 0 for no), hemoglobin (Hb, g/L), white blood cell…