Omics · study · 2026
Gene expression profile at single cell level of lymphocytes extracted from the mesenteric lymph nodes of TCRMOG animals colonized with either Salmonella expressing MOG or OVA
Listed in NCBI GEO
To analyze if expresion of a self-epitope (in this case an epitope of MOG (myleing oligodendrocyte glycoprotein)) in the gut can trigger an autoimmune reaction, TCRMOG (harbor MOG-reactive T cells) were colonized with a gut restricted strain of Salmonella expressing either an epitope of MOG or ovalbumin (OVA).
Description
We then compared the gene expression profile from immune cells within the mesenteric lymph node to assess (autoreactive) immune cell activation.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE243nnn/GSE243972 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE243972 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1020828 ncbi.nlm.nih.gov/bioproject/PRJNA1020828 ↗
project · from NCBI GEO
- PubMed 41437842 pubmed.ncbi.nlm.nih.gov/41437842 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE243972 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |