Constarium
← Search

Data · dataset · 2021

RISK11 signature scores for the biomarker-guided tuberculosis preventive therapy (CORTIS) randomised controlled trial

Listed in LSHTM Data Compass

RISK11 transcriptomic signature scores for 20,207 volunteers who were screened at five geographically diverse sites across South Africa.

Description

Signature scores were computed from QC'ed gene expression measurements performed by microfluidic RT-qPCR on mRNA derived from whole blood collected in PAXgene tubes. Participants were randomised into three groups and followed-up for 15 months to evaluate diagnostic and prognostic performance of RISK11 and to evaluate efficacy of high-dose isoniazid and rifapentine for prevention of incident TB.

Links

Where it is published

Catalogue records · 1

Topics

From keywords
Earth & Environmental Science · Humanities · Life Sciences · Medicine & Health · Social Science
Inferred from text
Oncology and carcinogenesis 72%

Related

Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
LSHTM Data Compassoai:datacompass.lshtm.ac.uk:211510 d agoJSON v1
FieldAssertionExtractorEvidence
concepts[field].anzsrc:group:3211enrichment · lshtm ac uktaxonomy-embedding@1.0.0title+keywords+description (72%)
concepts[field].local:field:earth-environmentalmapping · lshtm ac ukconnector:lshtm_ac_uk@1.0.0
concepts[field].local:field:humanitiesmapping · lshtm ac ukconnector:lshtm_ac_uk@1.0.0
concepts[field].local:field:life-sciencesmapping · lshtm ac ukconnector:lshtm_ac_uk@1.0.0
concepts[field].local:field:medicine-healthmapping · lshtm ac ukconnector:lshtm_ac_uk@1.0.0
concepts[field].local:field:social-sciencemapping · lshtm ac ukconnector:lshtm_ac_uk@1.0.0
descriptionsource · lshtm ac ukconnector:lshtm_ac_uk@1.0.0/metadata/dc/description
publication_datesource · lshtm ac ukconnector:lshtm_ac_uk@1.0.0
titlesource · lshtm ac ukconnector:lshtm_ac_uk@1.0.0/metadata/dc/title