Omics · study · 2026
Diurnal choroid plexus function in mice depends on sex, age, and amyloid-b status
Listed in NCBI GEO
The adult choroid plexus (ChP) produces the majority of cerebrospinal fluid (CSF), yet little is known about the biological and physiological factors that regulate the ChP under healthy conditions.
Description
CSF physiology is regulated by sleep and/or time of day and alters with age and in Alzheimer’s disease (AD), where sleep and circadian disruption often co-occur. We compare the transcriptome from mouse ChP in three conditions (young, aged, aged with amyloid b (Ab) pathology) collected at day and night.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE329nnn/GSE329540 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE329540 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1458142 ncbi.nlm.nih.gov/bioproject/PRJNA1458142 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- Disease 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE329540 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:disease | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |