Omics · study · 2026
DPM1 regulates ER-stress sensor IRE1 activity and antitumor immunity in colorectal cancer
Listed in NCBI GEO
This study investigates how DPM1 regulates the ER stress sensor IRE1 and how this impacts antitumor immunity in a colorectal cancer model.
Description
Single cell data were generated from tumor infiltrating T cells isolated from BALB/c mice bearing CT26 colorectal tumors. Wild-type and Dpm1 knockout tumors were profiled using 10x Genomics Chromium Single Cell 5' gene expression, feature barcode hashtags, and paired TCR VDJ libraries.
Raw reads are available in SRA under BioProject PRJNA1435810.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE324nnn/GSE324690 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE324690 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1435810 ncbi.nlm.nih.gov/bioproject/PRJNA1435810 ↗
project · from NCBI GEO
- PubMed 42230629 pubmed.ncbi.nlm.nih.gov/42230629 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus · Other
- From keywords
- Life Sciences
- Inferred from text
- Biochemistry and cell biology 68% · Cancer 75%
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE324690 | 11 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].anzsrc:group:3101 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (68%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[method].geo_series_type:other | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |