Omics · study · 2026
Methodological Considerations for Studying HOXA10, HOXA11 and LIF Expression in Unexplained Infertility: A Pilot Study in Colombian Women
Listed in NCBI GEO
This study investigates the transcriptomic profile of endometrial tissue from patients with idiopathic infertility, focusing on the expression of implantation- and inflammation-related genes, including HOXA10, HOXA11, and LIF, PKHD1L1, HS6ST1, LTF, CCDC1441.
Description
This study also focuses on identifying potential molecular markers that may be associated with unexplained infertility. RNA sequencing (RNA-seq) was performed to evaluate gene expression patterns and their potential association with impaired endometrial receptivity.
These data provide valuable insights into the molecular mechanisms underlying idiopathic infertility and represent a useful resource for further studies aimed at improving diagnosis and therapeutic strategies in reproductive medicine.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE328nnn/GSE328348 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE328348 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1454812 ncbi.nlm.nih.gov/bioproject/PRJNA1454812 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE328348 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |