Omics · study · 2026
The effects of oleic acid diet on ovarian cancer tumor growth in murine xenograft model
Listed in NCBI GEO
Oleic acid is an unsatuarated fatty acid that is converted by SCD1 (Stearoyl-CoA Desaturase 1), which is highly expressed in in ovarian cancer and has protective effect on cancer cell survival.
Description
We here report oleic acid high diet has upregulated serveral cell cycle related pathways such as E2F targets, mitotic spindle and G2M targets to promote cell proliferation in murine xenograft model.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE315nnn/GSE315189 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE315189 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1395100 ncbi.nlm.nih.gov/bioproject/PRJNA1395100 ↗
project · from NCBI GEO
- PubMed 42025693 pubmed.ncbi.nlm.nih.gov/42025693 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- Cancer 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE315189 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |