Omics · study · 2026
DNMT3L crosstalk with piRNA biogenesis in postnatal spermatogonial progenitor cells
Listed in NCBI GEO
We analyzed small RNAs expression profiles of different developmental stages (0 dpp and 8 dpp) to investigate the potential role of DNMT3L in spermatogonial stem cells.
Description
We observed that the relative proportion of microRNA and piRNA were similar between wild-type and Dnmt3l knockout mice. However, piRNA origin and composition significantly differed in 8 dpp Dnmt3l-deficiency samples, and the genomic location of predicted precursors remarkably shifted as well.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE313nnn/GSE313665 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE313665 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1380485 ncbi.nlm.nih.gov/bioproject/PRJNA1380485 ↗
project · from NCBI GEO
- PubMed 42277881 pubmed.ncbi.nlm.nih.gov/42277881 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Mus musculus · Non-coding RNA profiling by high throughput sequencing
- From keywords
- Life Sciences
- Inferred from text
- Genetics 70%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE313665 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].anzsrc:group:3105 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (70%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:non-coding-rna-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |