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Excel · study · 2026

CRISPR-Cas9 screen identify IGF2BP1 as a top, essential MYCN-synergizing candidate in the 17q-gain region

Listed in NCBI GEO

To systemically identify potential, crucial gene(s) in 17q-gain that contribute to MYCN-amplified neuroblastoma, we conducted an unbiased CRISPR-based negative selection screen from 17q21-ter locus genes in MYCN-amp/17q-gain neuroblastoma NLF cells.

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Homo sapiens · Other
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Life Sciences
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Genetics 68%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE33342611 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].anzsrc:group:3105enrichment · NCBI GEOtaxonomy-embedding@1.1.0title+keywords+description (68%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:othersource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title