Omics · study · 2026
Genotype-phenotype relationships (VPA/CHIR99021 vs. control; p53 Null vs. WT) in bulk RNA-sequencing of small intestinal murine organoids [bulk RNA-seq]
Listed in NCBI GEO
WT and Trp53 knock-out small intestinal organoids were cultured in standard ENR medium or treated with VPA and CHIR99021 for 5 days.
Description
At the endpoint of the culture, RNA was extracted from the cells and analysed with paired-end RNA-sequencing.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE218nnn/GSE218337 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE218337 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA903178 ncbi.nlm.nih.gov/bioproject/PRJNA903178 ↗
project · from NCBI GEO
- PubMed 42608409 pubmed.ncbi.nlm.nih.gov/42608409 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE218337 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |