Omics · study · 2026
Natural compounds magnolol and dicoumarol enhance adipogenesis for food production
Listed in NCBI GEO
Adipogenic enhancers have potential applications in the production of engineered adipose tissue for future foods and in the study of adipocyte biology.
Description
To investigate the molecular mechanisms underlying adipogenic enhancement, RNA sequencing was performed on murine 3T3-L1 cells and porcine dedifferentiated fat (DFAT) cells undergoing adipogenic differentiation. Cells were treated with vehicle control, magnolol, dicoumarol, magnolol plus dicoumarol, or rosiglitazone.
Transcriptomic profiling was conducted to characterize gene expression changes associated with enhanced lipid accumulation and adipocyte differentiation across species.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE336nnn/GSE336373 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE336373 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1481337 ncbi.nlm.nih.gov/bioproject/PRJNA1481337 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus · Sus scrofa
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE336373 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| concepts[organism].NCBITaxon:9823 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |