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Omics · study · 2026

Cell culture effects on isolated fibrotic lung CD103+ DCs

Listed in NCBI GEO

The trypophan metabolite kynurenine is a well known AHR ligand and drives inflammatory AHR respones, especially in dendritic cels.

Description

Ex vivo studies of dendrtic cells are complicated by the fact that culture conditions do not reproduce complex tissue microenvironments. To study these effects we compared transcriptomes of CD103+ lung DCs isolated from mice with blm-induced fibrosis and compared with DCs that had been cultured in standard culture media for 18h.

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Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE33879114 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title