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Excel · study · 2026

Human milk oligosaccharide 2’-fucosyllactose and lacto-n-neo-tetraose attenuate early-weaning-induced intestinal barrier dysfunction via gut microbiota modulation in mice

Listed in NCBI GEO

Early weaning is a common practice among young mothers and is associated with an increased risk of gastrointestinal disorders.

Description

Human milk oligosaccharides (HMOs) play a critical role in maintaining gut barrier integrity and have been increasingly applied in infant formulas. However, the mechanisms of HMOs in maintaining gut function remain unclear.

This study aimed to assess the effects of 2'-fucosyllactose (2'-FL) and Lacto-N-neotetraose (LNnT) in a mouse model of early weaning.

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Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE30339314 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title