Omics · study · 2026
Comparison of NK cell transcriptomes between C57BL6 and NOD mouse strains
Listed in NCBI GEO
Natural Killer (NK) cells are essential for surveillance of stressed, infected and malignant cells in the body.
Description
The autoimmune diabetes prone nonobese diabetic (NOD) mouse has a deficiency and dysfunction of NK cells compared to other strains but the molecular basis remains unclear. Here we performed bulk mRNA-seq on bead enriched splenic NK cells from early disease prediabetic 8 week-old female NOD mice as compared with age-matched C57BL6 female mice as controls.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE342nnn/GSE342137 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE342137 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1505654 ncbi.nlm.nih.gov/bioproject/PRJNA1505654 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- Disease 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE342137 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:disease | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |