Omics · study · 2026
Study on the effects of inflammatory cytokine IL‑1β stimulation on hepatocellular carcinoma cells
Listed in NCBI GEO
This transcriptome‑sequencing‑based study was performed to explore the transcriptional alterations triggered by stimulation with the inflammatory cytokine IL‑1β in human HCC cells.
Description
IL‑1β‑treated and vehicle‑control cell samples were harvested after 24 h of stimulation for total RNA extraction, strand‑specific library construction and high‑throughput RNA‑seq profiling. This dataset was generated to investigate the wide‑ranging biological impacts of IL‑1β‑mediated inflammatory signaling on hepatocellular carcinoma cells, and to provide transcriptomic resources for subsequent exploration of inflammation‑associated molecular events, functional pathways and candidate regulatory genes.
All raw sequencing reads from this project have been deposited in the NCBI SRA database for public re‑analysis.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE343nnn/GSE343712 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE343712 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1512435 ncbi.nlm.nih.gov/bioproject/PRJNA1512435 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Sequencing 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE343712 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |