Omics · study · 2026
The long noncoding RNA C1QTNF1-AS1 interacts with RSRC2 to ensure mitotic fidelity
Listed in NCBI GEO
Chromosome congression, a process of chromosome alignment at the spindle equator, is a key step in cell division.
Description
While much work has addressed the role of protein networks in controlling cell division, we have very little understanding how long noncoding RNAs (lncRNAs) and RNA binding proteins (RBPs) contribute to the fidelity of cell division. To investigate the role of lncRNA C1QTNF1-AS1 and its interacting protein partner RSRC2 in cell division, we depleted C1QTNF1-AS1 and RSRC2 with LNA gapmers and siRNAs, respectively, in HCT116 cells and analysed their impact on gene expression and splicing alterations.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE284nnn/GSE284007 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE284007 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1196826 ncbi.nlm.nih.gov/bioproject/PRJNA1196826 ↗
project · from NCBI GEO
- PubMed 41841495 pubmed.ncbi.nlm.nih.gov/41841495 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Genetics 73%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE284007 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].anzsrc:group:3105 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (73%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |