Omics · study · 2026
The KDM1A and KDM7A lysine demethylases cooperate to regulate androgen receptor function in prostate cancer cells [KDM1A & KDM7A inhibitors]
Listed in NCBI GEO
KDM1A and KDM7A are Androgen Receptor coregulators.
Description
Here the KDM1A and KDM7A inhibitors, namoline and TCE-5002 were used to pharmacologically inhibit KDM1A and KDM7A in prosate cancer cells and the effect on androgen regulated gene expression and splicing determined.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE194nnn/GSE194279 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE194279 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA800050 ncbi.nlm.nih.gov/bioproject/PRJNA800050 ↗
project · from NCBI GEO
- PubMed 41870972 pubmed.ncbi.nlm.nih.gov/41870972 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Cancer 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE194279 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |