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Omics · study · 2026

Linc01446 contributes to ferroptosis defence and progression of esophageal squamous cell carcinoma by regulating APEX1

Listed in NCBI GEO

Esophageal squamous cell carcinoma (ESCC) is a frequent malignant tumor worldwide, especially in China.

Description

The concrete mechanisms involved in the progression of ESCC remain elusive. Ferroptosis is a novel type of programmed cell death whose functions in ESCC is to be defined.

Thus, we analyzed the differential genes involved in ferroptosis of ESCC. Then, we screened the crucial gene and determine its function and related mechanisms.

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From keywords
Life Sciences
Inferred from text
Cancer 65%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE28363214 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[disease].local:disease:cancerenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title