Omics · study · 2026
The role of RNA-helicase MOV10 in the regulation of transcript levels during the development of mouse brain.
Listed in NCBI GEO
It has previously been shown that MOV10 exhibits a distinct developmental expression pattern, with protein levels being very high in the brains of neonatal mice and almost completely absent in adult brains.
Description
To investigate the role of MOV10 in brain development, we generated a mouse model called Mov10 Deletion by crossing a Mov10 conditional knockout line with Emx1-Cre and a Mov10 heterozygous mutant. In this study, we performed bulk RNA sequencing on whole brain tissue collected from wild-type (WT) and Mov10 Deletion mice at postnatal days 0, 7, 14, and 23.
The RNA extraction, library preparation, and sequencing was performed by Biostate.ai.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE317nnn/GSE317128 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE317128 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1406135 ncbi.nlm.nih.gov/bioproject/PRJNA1406135 ↗
project · from NCBI GEO
- PubMed 42239320 pubmed.ncbi.nlm.nih.gov/42239320 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE317128 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |