Omics · study · 2026
microRNA-497-5p-based Screening Identifies a Novel Synthetic Lethal-type Interaction via PKMYT1 and WEE1 in Pleural Mesothelioma
Listed in NCBI GEO
We discovered direct targets of miR-497-5p through biotinylated miRNA pull-down of target mRNA molecules from a epithelial subtype derived diffuse pleural mesothelioma (DPM) cell line (H2052).
Description
The pulldowns were done side by side with RNA-seq to capture the effects of miRNA on the transcriptomes of the DPM cells.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE282nnn/GSE282870 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE282870 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1190910 ncbi.nlm.nih.gov/bioproject/PRJNA1190910 ↗
project · from NCBI GEO
- PubMed 40673159 pubmed.ncbi.nlm.nih.gov/40673159 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens · Other
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 65%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE282870 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[method].geo_series_type:other | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |