Omics · study · 2026
Transcriptomic profiling of small intestine from irinotecan-treated wild-type and Gsdme-deficient mice
Listed in NCBI GEO
Irinotecan (CPT-11) is a topoisomerase I inhibitor that is widely used for solid tumors, including colorectal and pancreatic cancers.
Description
Although irinotecan exerts potent antitumor effects, it also causes intestinal mucositis. In the present study, the effect of irinotecan on intestinal mucositis was investigated in wild-type and Gsdme-deficient mice.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE342nnn/GSE342329 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE342329 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1507375 ncbi.nlm.nih.gov/bioproject/PRJNA1507375 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE342329 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |