Omics · study · 2026
Aldehyde dehydrogenase 2 deficiency exacerbates alcohol-associated liver fibrosis
Listed in NCBI GEO
This study investigates the role of Aldehyde Dehydrogenase 2 (ALDH2) in the pathogenesis of liver fibrosis.
Description
We performed gene expression profiling of liver tissues from wild-type (WT) and Aldh2 knockout mice subjected to a chronic fibrosis model. This dataset aims to identify molecular mechanisms and transcriptomic alterations associated with ALDH2 deficiency in the context of alcohol- and CCl4-induced liver fibrosis.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE317nnn/GSE317551 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE317551 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1414450 ncbi.nlm.nih.gov/bioproject/PRJNA1414450 ↗
project · from NCBI GEO
- PubMed 42516252 pubmed.ncbi.nlm.nih.gov/42516252 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE317551 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |