Imaging · study · 2026
Spatial transcriptomic sequencing of day 7 tumors in G422TN-GBM model
Listed in NCBI GEO
Glioblastoma are difficult to treat because they recur quickly after treatment caused by highly aggressive tumor cells at the distal end of the tumor entity.
Description
We created a new G422TN-GBM (TN: triple negative, i.e., wild type IDH1/2, chromosome1/19 Intact and wild type TERT-promoter) model that is highly consistent with the pathological features, immune response and therapeutic response of GBM. Based on this model, we performed spatial transcriptome of intravranial G422TN-tumor at day 7 post implantaion of G422TN-cells.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE253nnn/GSE253428 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE253428 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1065783 ncbi.nlm.nih.gov/bioproject/PRJNA1065783 ↗
project · from NCBI GEO
- PubMed 42474078 pubmed.ncbi.nlm.nih.gov/42474078 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Mus musculus · Other
- From keywords
- Life Sciences
- Inferred from text
- Cancer 65% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE253428 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:other | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |