Omics · study · 2026
Transcriptome profiling by RNA-seq was performed on HCCLM3 cells stably transfected with a PON1-overexpressing lentivirus (PON1-OE) and its negative control (PON1-NC).
Listed in NCBI GEO
The full-length human PON1 coding sequence was cloned into a lentiviral overexpression vector and used to infect low-expressing HCCLM3 cells.
Description
Stable overexpression clones (PON1-OE) and empty vector control clones (PON1-NC) were selected and maintained using puromycin.Each group is set up with three biological replicates.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE322nnn/GSE322594 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE322594 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1430687 ncbi.nlm.nih.gov/bioproject/PRJNA1430687 ↗
project · from NCBI GEO
- PubMed 42352243 pubmed.ncbi.nlm.nih.gov/42352243 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Agricultural biotechnology 69% · RNA sequencing 65%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE322594 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].anzsrc:group:3001 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (69%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |