Omics · study · 2026
Functional characterization of Central Nervous System (CNS) and peripheral immune responses in Alzheimer's Disease after Bacillus Calmette Guerin (BCG) vaccination in older adults.
Listed in NCBI GEO
Description
Cerebrospinal Fluid cells collected from older adults before and after BCG vaccination were studied for evaluating celltype specific functional responsivity to stimulation with antigens. Peripheral blood mononuclear cells were also studied to compare the peripheral and central nervous system (CNS) responsivities.This datase is part of the following. NCT04507126 - A Pilot Study of the Effects of Bacillus Calmette-Guérin (BCG) Immunization on Cerebrospinal Fluid and Blood-based Biomarkers in Older Adults - ClinicalTrials.gov. clinicaltrials.gov/ct2/show/NCT04507126 NCT05004688 - A Trial to Evaluate the Effects of BCG in Adults With MCI and Mild-to-Moderate AD - - ClinicalTrials.gov. clinicaltrials.gov/ct2/show/NCT05004688
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE280nnn/GSE280720 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE280720 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1180096 ncbi.nlm.nih.gov/bioproject/PRJNA1180096 ↗
project · from NCBI GEO
- PubMed 42393277 pubmed.ncbi.nlm.nih.gov/42393277 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Disease 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE280720 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:disease | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |