Data and files for "Drosophila Cryptochrome C-terminus binds FAD to mediate magnetosensitivity."

<p dir="ltr">This is the data for "Drosophila Cryptochrome C-terminus binds FAD to mediate magnetosensitivity", submitted for publication in PNSA Nexus and currently under revision.</p><p dir="ltr">Magnetosensitivity in animals has been proposed to involve a Cryptochrome (CRY)-based radical pair mechanism, although the molecular basis of this process remains unclear. The C-terminal fragment of <i>Drosophila</i> CRY (DmCRY-CT), which lacks the canonical FAD-binding pocket and conserved tryptophan residues associated with the canonical mechanism, is nevertheless sufficient to support magnetosensitivity.

This dataset contains all-atom molecular dynamics (MD) simulations investigating the interaction of flavin adenine dinucleotide (FAD) with DmCRY-CT and the effects of mutations selected based on the predicted contribution of specific residues to FAD binding. The deposited simulations provide structural and dynamic information on FAD–peptide interactions across wild-type and mutant systems.</p>