305 datasets

NCL Data2026 · dataset

<p>ANOVA outputs for the DGRP lines and for the RNAi validation experiments.</p> <p>(XLSX)</p>

NCL Data2026 · dataset

<p>Raw heart rate measurements and descriptive statistics for the 154 DGRP lines under control and salt-supplemented conditions.</p> <p>(XLSX)</p>

NCL Data2026 · dataset

<p>Raw data, descriptive statistics, ANOVAs, and Dunnett’s test results for the additional experiments assessing candidate genes with independent GD RNAi lines and the VDRC 60101 control (40D insertion-associated controls).</p> <p>(XLSX)</p>

NCL Data2026 · dataset

<p>List of RNAi lines used in the validation experiments and the viability status of each cross.</p> <p>(XLSX)</p>

NCL Data2026 · dataset

<p>R scripts implementing the genome-wide association analysis pipeline, including variant filtering and the FaST-LMM mixed-model association testing.</p> <p>(R)</p>

NCL Data2026 · dataset

<p>Top-variant annotations, candidate genes, and Gene Ontology terms identified in the genome-wide association analyses.</p> <p>(XLSX)</p>

NCL Data2026 · dataset

<p>Raw heart rate data and descriptive statistics for the RNAi validation crosses.</p> <p>(XLSX)</p>

NCL Data2026 · dataset

<p>R scripts used to perform the statistical analyses (descriptive statistics, ANOVA, mixed-effects models, Welch’s t-tests, and the RNAi validation tests) and to generate the figures.</p> <p>(R)</p>

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

Introduction<p>Sleep deprivation is increasingly recognized as a major health concern and is associated with impaired physiological and neurological functions. Panax ginseng C. A. Mey. has long been used to improve sleep quality; however, the limited availability and long cultivation cycle of natural ginseng restrict its sustainable utilization. Wild ginseng adventitious roots (ADV), produced via

DMU Figshare + UCL Research Data Repository + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

<div> <p>Background</p><p>Excess dietary sugar is a major contributor to metabolic disorders, including type 2 diabetes mellitus (T2DM). This study investigates the physiological, biochemical, behavioral, and molecular effects of high-sucrose diets in <i>Drosophila melanogaster</i> and evaluates the modulatory effects of metformin under these conditions.</p> <p>Methods</p><p>Flies were reared on n

DMU Figshare + UCL Research Data Repository2026 · dataset

<p>Bar graph showing mean SOD activity normalized to total protein (± SD) across NC, S5, S15, SM5, and SM15 groups. Both sucrose-only groups showed significantly reduced SOD activity relative to NC. SM5 showed a non-significant increase relative to S5, whereas SM15 showed a significant increase relative to S15, although activity remained below NC. Data represent three independent biological experi

DMU Figshare + UCL Research Data Repository2026 · dataset

<p>Both sucrose-only groups showed significantly reduced expression relative to NC. SM5 showed a non-significant increase relative to S5, whereas SM15 showed a significant increase relative to S15. Expression was normalized to RpS20, and NC served as the calibrator. Data represent three independent biological experiments. *P < 0.05 versus NC; #P < 0.05 for S5 versus SM5 or S15 versus SM15, as appl

DMU Figshare + UCL Research Data Repository2026 · dataset

<div> <p>Background</p><p>Excess dietary sugar is a major contributor to metabolic disorders, including type 2 diabetes mellitus (T2DM). This study investigates the physiological, biochemical, behavioral, and molecular effects of high-sucrose diets in <i>Drosophila melanogaster</i> and evaluates the modulatory effects of metformin under these conditions.</p> <p>Methods</p><p>Flies were reared on n

DMU Figshare + UCL Research Data Repository + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

<div> <p>Background</p><p>Excess dietary sugar is a major contributor to metabolic disorders, including type 2 diabetes mellitus (T2DM). This study investigates the physiological, biochemical, behavioral, and molecular effects of high-sucrose diets in <i>Drosophila melanogaster</i> and evaluates the modulatory effects of metformin under these conditions.</p> <p>Methods</p><p>Flies were reared on n

DMU Figshare + UCL Research Data Repository2026 · dataset

<p>Both sucrose-only groups showed significantly reduced expression relative to NC. SM5 showed a non-significant increase relative to S5, whereas SM15 showed a significant increase relative to S15. Expression was normalized to RpS20, and NC served as the calibrator. Data represent three independent biological experiments. *P < 0.05 versus NC; #P < 0.05 for S5 versus SM5 or S15 versus SM15, as appl

DMU Figshare + UCL Research Data Repository2026 · dataset

<p>Both sucrose-only groups showed significantly reduced expression relative to NC. SM5 showed a non-significant increase relative to S5, whereas SM15 showed a significant increase relative to S15. Expression was normalized to RpS20, and NC served as the calibrator. Data represent three independent biological experiments. *P < 0.05 versus NC; #P < 0.05 for S5 versus SM5 or S15 versus SM15, as appl

DMU Figshare + UCL Research Data Repository + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

<div> <p>Background</p><p>Excess dietary sugar is a major contributor to metabolic disorders, including type 2 diabetes mellitus (T2DM). This study investigates the physiological, biochemical, behavioral, and molecular effects of high-sucrose diets in <i>Drosophila melanogaster</i> and evaluates the modulatory effects of metformin under these conditions.</p> <p>Methods</p><p>Flies were reared on n

DMU Figshare + UCL Research Data Repository2026 · dataset

<p>Bar graph showing mean GST activity (mU/mg protein ± SD) across NC, S5, S15, SM5, and SM15 groups. Both sucrose-only groups showed significantly reduced GST activity relative to NC. SM5 showed a non-significant increase relative to S5, whereas SM15 showed a significant increase relative to S15. Data represent three independent biological experiments. *P < 0.05 versus NC; #P < 0.05 for S5 versus

DMU Figshare + UCL Research Data Repository2026 · dataset

<p>Both sucrose-only groups showed significantly reduced expression relative to NC. SM5 showed a non-significant increase relative to S5, whereas SM15 showed a significant increase relative to S15. Expression was normalized to RpS20, and NC served as the calibrator. Data represent three independent biological experiments. *P < 0.05 versus NC; #P < 0.05 for S5 versus SM5 or S15 versus SM15, as appl

DMU Figshare + UCL Research Data Repository + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

<div> <p>Background</p><p>Excess dietary sugar is a major contributor to metabolic disorders, including type 2 diabetes mellitus (T2DM). This study investigates the physiological, biochemical, behavioral, and molecular effects of high-sucrose diets in <i>Drosophila melanogaster</i> and evaluates the modulatory effects of metformin under these conditions.</p> <p>Methods</p><p>Flies were reared on n

DMU Figshare + UCL Research Data Repository2026 · dataset

<p>Bar graph showing mean survival rate (± SD) across NC, S5, S15, SM5, and SM15 groups. Both sucrose-only groups showed significantly reduced survival relative to NC. SM5 showed a non-significant increase relative to S5, whereas SM15 showed a significant improvement relative to S15. Data represent three independent biological experiments. *P < 0.05 versus NC; #P < 0.05 for S5 versus SM5 or S15 ve

DMU Figshare + UCL Research Data Repository2026 · dataset

<p>Both sucrose-only groups showed significantly reduced expression relative to NC. SM5 showed a non-significant increase relative to S5, whereas SM15 showed a significant increase relative to S15. Expression was normalized to RpS20, and NC served as the calibrator. Data represent three independent biological experiments. *P < 0.05 versus NC; #P < 0.05 for S5 versus SM5 or S15 versus SM15, as appl

DMU Figshare + UCL Research Data Repository + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

<div> <p>Background</p><p>Excess dietary sugar is a major contributor to metabolic disorders, including type 2 diabetes mellitus (T2DM). This study investigates the physiological, biochemical, behavioral, and molecular effects of high-sucrose diets in <i>Drosophila melanogaster</i> and evaluates the modulatory effects of metformin under these conditions.</p> <p>Methods</p><p>Flies were reared on n

DMU Figshare + UCL Research Data Repository + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

<div> <p>Background</p><p>Excess dietary sugar is a major contributor to metabolic disorders, including type 2 diabetes mellitus (T2DM). This study investigates the physiological, biochemical, behavioral, and molecular effects of high-sucrose diets in <i>Drosophila melanogaster</i> and evaluates the modulatory effects of metformin under these conditions.</p> <p>Methods</p><p>Flies were reared on n

DMU Figshare + UCL Research Data Repository + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

<div> <p>Background</p><p>Excess dietary sugar is a major contributor to metabolic disorders, including type 2 diabetes mellitus (T2DM). This study investigates the physiological, biochemical, behavioral, and molecular effects of high-sucrose diets in <i>Drosophila melanogaster</i> and evaluates the modulatory effects of metformin under these conditions.</p> <p>Methods</p><p>Flies were reared on n