Excel · study · 2026
Whole-genome microarray profiling of nutrient-deprived medium (NDM) in human PANC-1 pancreatic cancer cells
Listed in NCBI GEO
Pancreatic ductal adenocarcinoma cells often encounter nutrient deprivation in the tumor microenvironment and are thought to adapt by altering the expression of multiple genes.
Description
However, comprehensive time-resolved profiling of transcriptional responses under nutrient-deprived conditions remains limited. Here, we performed whole-genome microarray expression profiling to characterize gene expression changes in the human pancreatic cancer cell line PANC-1 cultured in nutrient-deprived medium.
The dataset captures dynamic nutrient stress–associated gene sets and metabolic remodeling, including induction of genes linked to pentose phosphate pathway–related adaptation (e.g., TKTL1). This dataset provides a resource for studying transcriptional dynamics underlying pancreatic cancer cell survival under nutrient deprivation.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE316nnn/GSE316783 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE316783 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1404203 ncbi.nlm.nih.gov/bioproject/PRJNA1404203 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by array · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE316783 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].anzsrc:group:3105 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (73%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |