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Spectroscopic and DNA interaction studies on mixed ligand copper(II) complexes of dicyanamide with ethylenediamine or 1,3-diaminopropane

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Mixed ligand copper(II) complexes of dicyanamide with different polyamines, viz. ethylenediamine ( 1 ) and 1,3-diaminopropane ( 2 ), have been synthesized and characterized.

Description

The crystal structure of complex 1 contains a five-coordinated copper in a distorted square-pyramidal environment and forms 1D zig-zag polymeric chain via the bridging ligand dicyanamide. Hydrogen bonding contributes supramolecular architecture in the crystal.

Electronic spectral studies suggest the distorted square-pyramidal structure of the complexes. The interaction of the copper(II) complexes with calf-thymus DNA reveals nonintercalative binding mode. The two complexes have antimicrobial activity against the bacteria ( viz.

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Salmonella paratyphi ), which is responsible for paratyphoid fever.

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DataCite10.6084/m9.figshare.350356713 d agoJSON v1
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