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Data · dataset · 2016

Spectroscopic and DNA Interaction Studies on Mixed Ligand Copper(II) Complexes of Dicyanamide with ethylenediamine or 1,3-diaminopropane

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Mixed ligand copper(II) complexes of dicyanamide with different polyamines viz . ethylenediamine ( 1 ) and 1,3-diaminopropane ( 2 ) have been synthesized and characterized.

Description

The crystal structure of complex ( 1 ) contains a five coordinated copper in a distorted square pyramidal environment and forms 1D zig-zag polymeric chain via the bridging ligand dicyanamide. Hydrogen bonding contributes supramolecular architecture in the crystal.

Electronic spectral studies suggest the distorted square pyramidal structure of the complexes. The interaction of the copper(II) complexes with Calf Thymus(CT)-DNA reveals non-intercalative binding mode. The two complexes have antimicrobial activity against the bacteria ( viz. salmonella paratyphi ) which is responsible for paratyphoid fever.

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Topics

From keywords
Cancer · Microbiology
Inferred from text
Computed tomography 50%

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Provenance · 1 source records, 14 field assertions
SourceKeyLast seenRaw
DataCite10.6084/m9.figshare.3503567.v113 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · DataCiteconnector:datacite@1.0.0/data/attributes/rightsList
byte_sizesource · DataCiteconnector:datacite@1.0.0
concepts[disease].local:disease:cancermapping · DataCitevocabulary-mapper@1.0.0keywords['Cancer']
concepts[field].fos:biological-sciencessource · DataCiteconnector:datacite@1.0.0
concepts[field].fos:chemical-sciencessource · DataCiteconnector:datacite@1.0.0
concepts[field].fos:health-sciencessource · DataCiteconnector:datacite@1.0.0
concepts[field].fos:physical-sciencessource · DataCiteconnector:datacite@1.0.0
concepts[modality].local:modality:ctenrichment · DataCitekeyword-concept-rules@1.0.0title+description (50%)
created_datesource · DataCiteconnector:datacite@1.0.0
descriptionsource · DataCiteconnector:datacite@1.0.0/data/attributes/descriptions
licensesource · DataCiteconnector:datacite@1.0.0/data/attributes/rightsList
publication_datesource · DataCiteconnector:datacite@1.0.0/data/attributes/dates
titlesource · DataCiteconnector:datacite@1.0.0/data/attributes/titles/0/title
updated_datesource · DataCiteconnector:datacite@1.0.0