Differential chromatin accessability in follicular B cells, marginal zone B cells and newly formed plasma cells. [ATAC-Seq]

We sought to determine differences in chromatin accessability at plasma cell program-relevant loci between these cells and follicular B cells also located within the spleen but less receptive to Notch signaling. To ths end, we prepared ATAC-seq libriaries from steady state marginal zone and follicular B cells as well as newly formed plasma cells generated in Blimp1GFP/+ reporter mice 4 days post immunization with LPS.