Omics · study · 2026
Integrative Transcriptomics Identifies Trazodone as a Modulator of Urban Particulate Matter-Induced Neuroinflammation
Listed in NCBI GEO
Urban particulate matter (UPM) triggers neuroinflammation through microglial activation, contributing to the progression of neurodegenerative diseases; however, effective therapeutic interventions remain limited.
Description
In this study, we investigated the inhibitory effects of trazodone (TZ), a clinically approved antidepressant, on UPM-induced neuroinflammation using transcriptomic analyses.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE336nnn/GSE336648 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE336648 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1482153 ncbi.nlm.nih.gov/bioproject/PRJNA1482153 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE336648 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |