Cxcr2 deficiency alters transcriptional programs in articular cartilage and subchondral bone of adult male mice

We profiled gene expression in femoral head articular cartilage and knee subchondral bone from adult male Cxcr2-null mice and wild-type littermate controls using Clariom S Mouse microarrays. The microarray dataset is part of a multi-tissue study linking Cxcr2 deficiency to altered bone microarchitecture and coordinated, tissue-specific transcriptional remodeling in bone marrow, articular cartilage, and subchondral bone.