Omics · study · 2026
INHBA activated PI3K/AKT pathway in gastric cancer cell line MKN45
Listed in NCBI GEO
The gastric cancer cell' migration ability, invasion ability and the tumor growth could be promoted by INHBA.
Description
To investigate the mechanism underlying the regulation of INHBA in promoting gastric cancer progression, high-throughput sequencing was carried in gastric cancer cell line MKN45.The results showed that PI3K/AKT pathway was activated by INHBA. Which indicated that INHBA regulated gastric cancer progression by activating PI3K/AKT pathway.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE277nnn/GSE277561 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE277561 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1162811 ncbi.nlm.nih.gov/bioproject/PRJNA1162811 ↗
project · from NCBI GEO
- PubMed 41540191 pubmed.ncbi.nlm.nih.gov/41540191 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Cancer 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE277561 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |