Omics · study · 2026
Effect of WM-3835 treatment and HBO1 S50/53A mutation on gene expression of OMM2.3 cells
Listed in NCBI GEO
To investigate the changes in gene expression profiles in OMM2.3 cells induced by WM-3835, we treated OMM2.3 cells with 20μM WM-3835 for 48 hours; To investigate the changes in gene expression profiles in OMM2.3 cells after HBO1 S50/53A mutaion, we established Flag_HBO1 and Flag_HBO1S50/53A overexpressed cell lines.
Description
We then performed gene expression profiling analysis using data obtained from RNA-seq of 4 different cell lines with two replicates.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE299nnn/GSE299365 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE299365 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1273976 ncbi.nlm.nih.gov/bioproject/PRJNA1273976 ↗
project · from NCBI GEO
- PubMed 42575441 pubmed.ncbi.nlm.nih.gov/42575441 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Genetics 69% · RNA sequencing 65%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE299365 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].anzsrc:group:3105 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (69%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |