Transcriptomes of human whole blood cells in sepsis patients

Sepsis is a severe systemic infection that often leads to multiple organ dysfunction. Its pathogenesis is complex and involves the abnormal activation of various cellular and molecular pathways.

By analyzing the transcriptomes of whole blood cells in sepsis patients through sequencing, we aim to reveal the key changes in gene expression and their potential regulatory mechanisms during the onset and progression of sepsis. The study included sepsis patients with different underlying diseases and also set up a healthy control group for comparative analysis.