Omics · study · 2026
OASL Regulates Endothelial Function via USP39-Mediated Deubiquitination of CDK1 to Promote Large Full-Thickness Skin Defect Healing
Listed in NCBI GEO
Large full-thickness skin defects (LFSDs) remain a major clinical challenge due to insufficient vascular regeneration and impaired tissue repair.
Description
Emerging evidence suggests that oligoadenylate synthase-like protein (OASL), an interferon-stimulated protein, contributes to endothelial homeostasis and vascular function; however, its role in endothelial regeneration and wound healing has not been elucidated. Here, we investigated the molecular mechanism by which OASL regulates endothelial regeneration and explored its therapeutic potential for LFSD repair.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE337nnn/GSE337629 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE337629 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1490524 ncbi.nlm.nih.gov/bioproject/PRJNA1490524 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE337629 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |