Omics · study · 2026
The Mechanism by Which HIF-2α Regulates Adipogenic Differentiation of BMSCs
Listed in NCBI GEO
The objective of this study was to investigate whether GLP-1 regulates the adipogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) and to elucidate the underlying molecular mechanism.
Description
Specifically, we aimed to determine if GLP-1 suppresses adipogenesis through modulation of the PI3K-AKT and HIF signaling pathways, and to verify the dependence of this regulatory effect on HIF-2α
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE305nnn/GSE305520 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE305520 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1306177 ncbi.nlm.nih.gov/bioproject/PRJNA1306177 ↗
project · from NCBI GEO
- PubMed 42425087 pubmed.ncbi.nlm.nih.gov/42425087 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE305520 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |