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Data · study · 2026

Gene expression profiling of Venetoclax-treated HL-60 cells

Listed in NCBI GEO

Venetoclax is a selective BCL-2 inhibitor with antileukemic activity.

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To investigate the transcriptional alterations induced by Venetoclax in human acute myeloid leukemia cells, HL-60 cells were treated with Venetoclax for 48 h and subjected to whole-transcriptome expression profiling using the GeneChip PrimeView Human Gene Expression Array. HL-60 cells were treated with 9.788 μM Venetoclax for 48 h.

HL-60 cells without Venetoclax treatment were used as controls. Total RNA was isolated from control and Venetoclax-treated cells, and biotin-labeled cRNA was prepared and hybridized to PrimeView Human Gene Expression Array chips.

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Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE34436214 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-arraysource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title