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Excel · study · 2026

Aging and the pathophysiology of pulmonary Mycobacterium avium complex (MAC) disease

Listed in NCBI GEO

We infected 18-month-old mice (old mice) and 9-week-old mice (young mice) with 1 × 10⁷ CFU of Mycobacterium avium via the respiratory tract for comparison analysis.

Description

Two months post-infection, both bacterial loads and mortality rates were significantly higher in old mice compared to young mice. RNA-seq analysis of lung tissues were performed.

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From keywords
Life Sciences
Inferred from text
Disease 75% · RNA sequencing 65%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE28750115 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[disease].local:disease:diseaseenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title