Data · dataset · 2025
Supplementary Fig. 9d-g | Metabolic profiling of ALS motor neurons
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This item is part of the Figshare
Description
Project
Early mitochondrial dysfunction revealed across FUS- and TARDBP-ALS at single cell resolution (su.figshare.com/projects/Early_mitochondrial_dysfunction_revealed_across_FUS-_and_TARDBP-ALS_at_single_cell_resolution/163252) From Data Availability Statement for the paper in Nature Communications entitled: Single-cell RNA sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS "We have deposited all raw and processed RNA sequencing data generated in this study on the NCBI Gene Expression Omnibus (GEO) under the accession number GSE226482.
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The C9orf72-ALS bulk RNA sequencing data was retrieved directly from the authors of the study. [Items under this Figshare Project contain:] "Scans of fluorescent western blots, raw imaging files from confocal microscopy, the analysis files from Opera Phenix, qPCR data sets, and Seahorse assay result files." -------------------------------------------- [Item specific description:] Metabolic profiling of in-vitro differentiated ALS motor neurons using Seahorse metabolic flux measurements.
The raw experimental files generated with the Seahorse XF flux analyser (Agilent). are in the proprietary file format ASYR. More information about the ASYR file format can be found here: agilent.com/cs/pubimages/misc/ReadMe_Wave_Desktop_2-6.pdf
Links
Where it is published
- DOI doi.org/10.17045/sthlmuni.22557340 ↗
DOI / persistent id · from researchdata se
Catalogue records · 1
- OAI-PMH record api.researchdata.se/oai-pmh?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3A… ↗
metadata API · from researchdata se
Topics
- From keywords
- Biochemistry and cell biology · Earth & Environmental Science · Life Sciences
- Inferred from text
- Imaging 75% · Microscopy 75% · RNA sequencing 75% · Sequencing 75% · Single-cell RNA sequencing 75%
Provenance · 1 source records, 12 field assertions
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| concepts[modality].local:modality:rna-seq | enrichment · researchdata se | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · researchdata se | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:single-cell-rna-seq | enrichment · researchdata se | keyword-concept-rules@1.0.0 | title+description (75%) |
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| title | source · researchdata se | connector:researchdata_se@1.0.0 | /metadata/dc/title |