Excel · study · 2026
IL-1β+ Macrophages Promote CD Intestinal Mucosal Barrier Injury by Inducing Ferroptosis in Intestinal Epithelial Cells
Listed in NCBI GEO
This RNA-seq dataset was generated to investigate transcriptomic changes in human intestinal epithelial cells co-cultured with IL-1β-low or IL-1β-high THP-1-derived macrophages.
Description
FHC and NCM460 cells were co-cultured with IL-1β⁻ Mac or IL-1β⁺ Mac, followed by RNA sequencing to identify gene expression changes associated with epithelial injury, oxidative stress, lipid peroxidation, and ferroptosis-related pathways.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE338nnn/GSE338571 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE338571 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1495198 ncbi.nlm.nih.gov/bioproject/PRJNA1495198 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE338571 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |