Excel · study · 2026
Importance of Golgi homeostasis in hair quality: Grasp55 is crucial for cuticle formation
Listed in NCBI GEO
The Golgi apparatus is a central hub for protein processing, trafficking, and secretion, and its integrity is essential for epidermal barrier function and hair follicle homeostasis.
Description
While Golgi dysfunction has been linked to skin and hair abnormalities, its direct contribution to hair shaft formation remains unclear. Here, we investigated the role of Golgi reassembly stacking protein 55 (GRASP55), a structural factor critical for cisternal stacking and membrane tethering, in hair biology.
We generated Grasp55 knockout (KO) mice and analyzed the ultrastructure and mechanical properties of their hair shafts.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE309nnn/GSE309302 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE309302 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1335115 ncbi.nlm.nih.gov/bioproject/PRJNA1335115 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE309302 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |