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Table · dataset · 2026

Source data underlying Figures 1–4: Persistent CCL3 expression sustains neutrophil recruitment and contributes to delayed wound healing in advanced age

Listed in figshare and Loughborough Research Repository — shown once because both records carry DOI 10.6084/m9.figshare.33985552.v1

Description

<p dir="ltr">This Excel workbook contains the numerical source data used to generate the graphs and quantitative analyses presented in Figures 1–4 of the associated study investigating age-associated differences in cutaneous wound healing and inflammatory responses.</p><p dir="ltr">Data are organised into individual worksheets according to figure and include measurements from young and aged mice. The workbook contains:</p><ul><li><b>Figure 1:</b> wound area measurements, scab presence, and epithelial gap measurements over the course of wound healing.</li><li><b>Figure 2:</b> quantification of wound-bed neutrophils and macrophages, together with analyses of neutrophil proximity to macrophages and the perivascular niche.</li><li><b>Figure 3:</b> Gene Ontology (GO) enrichment results, differential gene-expression data, and expression measurements for <b>Ccl3, Cxcl2, and Cxcl3</b> in young and age-impaired wounds.

Separate worksheets (<b>Figure 3D_young</b> and <b>Figure 3D_old</b>) contain gene-level log fold-change and adjusted P-value data used for the differential-expression analysis.</li><li><b>Figure 4:</b> quantification and cellular composition of CCL3⁺ cells, wound-healing measurements following CCL3-neutralising antibody treatment, wound-width measurements, and Ly6G⁺ neutrophil quantification.</li></ul><p dir="ltr">Values are provided at the level used for statistical analysis and/or generation of the corresponding graphs in the manuscript.

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Where applicable, individual columns or rows represent measurements from individual biological samples or experimental groups.</p><p dir="ltr">Abbreviations: DPI/dpw, days post-injury/days post-wounding; GO, Gene Ontology; DEG, differentially expressed gene.</p>

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figshareoai:figshare.com:article/3398555212 d agoJSON v1
Loughborough Research Repositoryoai:figshare.com:article/3398555211 d agoJSON v1
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