Table 1_Underwater hybrid ESD versus conventional ESD for colorectal laterally spreading tumors: a retrospective study.docx

Underwater hybrid ESD (U-Hybrid ESD) is an emerging technique. We compared the efficacy and safety of U-Hybrid ESD versus C-ESD for colorectal LSTs.</p>Methods<p>This exploratory, single-center retrospective study included 300 patients with LSTs ≥20 mm (U-Hybrid ESD, n = 150; C-ESD, n = 150).

Procedure time, postoperative hospital stay, time to resume oral diet, R0 resection rate, and adverse events were compared. Hypothesis-generating stratified analyses by lesion size and pathology were also performed.</p>Results<p>After multivariable adjustment, U-Hybrid ESD had significantly shorter procedure time (adjusted mean 21.29 vs. 31.99 min, adjusted mean difference −10.70, P < 0.001), shorter hospital stay (2.38 vs. 2.61 days, P = 0.008), and earlier oral diet (25.28 vs. 28.32 h, P = 0.004).