Data · study · 2026
Transcriptional profile of the murine epithelial boundary corresponding to the gastro-esophageal junction
Listed in NCBI GEO
Exposure of the gastro-esophageal junction (GEJ) to microenvironmental insults represents a significant risk factor for the induction of metaplastic changes of the esophageal epithelium (Barret’s esophagus) and for initiation of malignant transformation.
Description
Little is known about alterations of the genetic programme prior to a pathological manifestation and the use of rodent model systems has been limited due to specific anatomical characteristics.
This study was carried out to identify genes that are specifically up-regulated at the mouse squamocolumnar junction (SCJ), the epithelial boundary located at the limiting ridge that separates forestomach and corpus and that is morphologically analogous to the GEJ.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE16nnn/GSE16976 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE16976 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA117273 ncbi.nlm.nih.gov/bioproject/PRJNA117273 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by array · Mus musculus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE16976 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |