Constarium
← Search

Omics · study · 2026

PRMT5 activity sustains histone production to maintain genome integrity

Listed in NCBI GEO

Using time-resolved nascent transcriptional profiling, quantitative proteomics, and imaging, we show that PRMT5 activity is required to sustain histone transcription and histone protein synthesis during S phase.

Links

Get the data

Where it is published

Documentation and papers

Topics

Stated by source
Genome binding/occupancy profiling by high throughput sequencing · Homo sapiens
From keywords
Life Sciences
Inferred from text
Imaging 75% · Mass spectrometry 65%

Related

Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE33461112 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:genome-binding-occupancy-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:imagingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:mass-spectrometryenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title