Omics · study · 2026
Transcriptome of mouse colon under radiation injury and syringin treatment
Listed in NCBI GEO
This study performed transcriptome RNA sequencing on 15 mouse colon samples, including 5 blank control samples, 5 abdominal ionizing radiation (IR)-induced intestinal injury samples, and 5 syringin-treated injury samples.
Description
The aim was to identify gene expression changes and key regulatory pathways involved in radiation-induced intestinal damage and the protective mechanism of syringin. Differentially expressed genes (DEGs) were analyzed to explore mechanisms related to ferroptosis, the hnRNPA3-ESRRG-AIFM2-FSP1 regulatory axis, and gut-brain axis communication.
These data provide a valuable transcriptomic resource for understanding radiation-induced intestinal injury and the transcriptomic responses to syringin in mouse colon tissue.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE332nnn/GSE332752 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE332752 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1463021 ncbi.nlm.nih.gov/bioproject/PRJNA1463021 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE332752 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |